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RAB21 (基因名), Ras-related protein Rab-21 (蛋白名), rab21_bovin.
产品名称:

Bovine RAB21/ Ras-related protein Rab-21 ELISA Kit

货号:

E4720b

商标:
EIAab®
监管等级:
检测方法:
ELISA
特异性:
Natural and recombinant bovine Ras-related protein Rab-21
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Bovine RAB21 ELISA Kit
规格 & 价格: cart
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Bovine RAB21 ELISA Kit
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通用注释


亚单元:
Interacts with the cytoplasmic tail of integrins ITGA1, ITGA2, ITGA5, ITGA6, ITGA11 and ITGB1; this interaction is dependent upon its GDP/GTP cycle. Interacts with ANKRD27.


功能:
Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration. During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis (By similarity). Involved in neurite growth.


亚细胞位置:
Endoplasmic reticulum membrane Lipid-anchor Golgi apparatus Trans-Golgi network Golgi apparatus membrane Early endosome membrane Cytoplasmic vesicle membrane Cleavage furrow Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm. During mitosis, in mid-telophase, localized in the ingressing cleavage furrow. In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (By similarity).


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