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PTGDS (基因名), Prostaglandin-H2 D-isomerase (蛋白名), ptgds_canfa.
产品名称:

Dog PTGDS/ Prostaglandin-H2 D-isomerase ELISA Kit
前列腺素-H2D-异构酶

货号:

E0167d

商标:
EIAab®
监管等级:
别名:

Glutathione-independent PGD synthase, Lipocalin-type prostaglandin-D synthase, Prostaglandin-D2 synthase, PGD2 synthase, PGDS, PGDS2

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.625-40ng/mL
灵敏度:
0.268ng/mL
特异性:
Natural and recombinant dog Prostaglandin-H2 D-isomerase
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Metabolism
Dog PTGDS ELISA Kit
规格 & 价格: cart
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Dog PTGDS ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

85-95%

108-120%

94-104%

87-97%

EDTA plasma(n=5)

107-120%

85-95%

87-97%

93-103%

heparin plasma(n=5)

103-115%

 

107-117%

84-94%

98-107%

 

通用注释


亚单元:
Monomer.


功能:
Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.


亚细胞位置:
Rough endoplasmic reticulum Nucleus membrane Golgi apparatus Cytoplasm perinuclear region Secreted Detected on rough endoplasmic reticulum of arachnoid and menigioma cells. Localized to the nuclear envelope, Golgi apparatus, secretory vesicles and spherical cytoplasmic structures in arachnoid trabecular cells, and to circular cytoplasmic structures in meningeal macrophages and perivascular microglial cells. In oligodendrocytes, localized to the rough endoplasmic reticulum and nuclear envelope. In retinal pigment epithelial cells, localized to distinct cytoplasmic domains including the perinuclear region. Also secreted.


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