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PSMB5 (基因名), Proteasome subunit beta type-5 (蛋白名), psb5_chick.
产品名称:

Chicken PSMB5/ Proteasome subunit beta type-5 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Macropain chain 1, Multicatalytic endopeptidase complex chain 1, Proteasome chain 1, Proteasome subunit C1

检测方法:
ELISA
特异性:
Natural and recombinant chicken Proteasome subunit beta type-5
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Chicken PSMB5 ELISA Kit
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Chicken PSMB5 ELISA Kit
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通用注释


亚单元:
The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is a barrel-shaped complex made of 28 subunits that are arranged in four stacked rings. The two outer rings are each formed by seven alpha subunits, and the two inner rings are formed by seven beta subunits. The proteolytic activity is exerted by three beta-subunits PSMB5, PSMB6 and PSMB7. Directly interacts with POMP. Interacts with ABCB1 and TAP1.


功能:
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB5 displays a chymotrypsin-like activity.


亚细胞位置:
Cytoplasm Nucleus


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