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PRNP (基因名), Major prion protein homolog (蛋白名), prio_chick.
产品名称:

Chicken PRNP/ Major prion protein homolog ELISA Kit
主要朊蛋白同源物

货号:

E9345c

商标:
EIAab®
监管等级:
别名:

65-21 protein, Acetylcholine receptor-inducing activity, PR-LP, ARIA, PRN-P

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/mL
灵敏度:
0.095ng/mL
特异性:
Natural and recombinant chicken Major prion protein homolog
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Neurosciences
Chicken PRNP ELISA Kit
规格 & 价格: cart
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Chicken PRNP ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Monomer and homodimer. Has a tendency to aggregate into amyloid fibrils containing a cross-beta spine, formed by a steric zipper of superposed beta-strands. Soluble oligomers may represent an intermediate stage on the path to fibril formation. Copper binding may promote oligomerization.


功能:
Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains.


亚细胞位置:
Cell membrane Lipid-anchor GPI-anchor


该产品尚未在任何出版物中被引用。
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