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PDGFC (基因名), Platelet-derived growth factor C (蛋白名), pdgfc_human.
产品名称:

Human PDGFC/ Platelet-derived growth factor C ELISA Kit
血小板衍生生长因子C

货号:

E0528h

商标:
EIAab®
监管等级:
别名:

Fallotein, Spinal cord-derived growth factor, VEGF-E, SCDGF, UNQ174/PRO200, PDGF-C, SCDGF

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
78-5000pg/mL
灵敏度:
36pg/mL
特异性:
Natural and recombinant human Platelet-derived growth factor C
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cardiovascular
Human PDGFC ELISA Kit
规格 & 价格: cart
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Human PDGFC ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤6.2%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤10.6%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

102

96-108

Plasma

104

98-110

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

93-102%

89-99%

91-101%

104-115%

EDTA plasma(n=5)

95-104%

81-90%

111-120%

94-105%

heparin plasma(n=5)

99-109%

 

84-96%

84-96%

98-106%

 

通用注释


亚单元:
Homodimer; disulfide-linked. Interacts with PDGFRA homodimers, and with heterodimers formed by PDGFRA and PDGFRB. Interacts (via CUB domain) with PLAT (via kringle domain).


功能:
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling. Plays an important role in angiogenesis and blood vessel development. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function.


亚细胞位置:
Cytoplasm Cytosol Secreted Nucleus Cytoplasmic granule Cell membrane Sumoylated form is predominant in the nucleus (PubMed:15247255). Stored in alpha granules in platelets (PubMed:15061151).


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