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Pcsk1n (基因名), ProSAAS (蛋白名), pcsk1_rat.
产品名称:

Rat Pcsk1n/ ProSAAS ELISA Kit
ProSAAS

货号:

E4804r

商标:
EIAab®
监管等级:
别名:

Proprotein convertase subtilisin/kexin type 1 inhibitor, pro-SAAS, Proprotein convertase 1 inhibitor

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/mL
灵敏度:
0.168ng/mL
特异性:
Natural and recombinant rat ProSAAS
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Rat Pcsk1n ELISA Kit
规格 & 价格: cart
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Rat Pcsk1n ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts via the C-terminal inhibitory domain with PCSK1 65 kDa form.


功能:
May function in the control of the neuroendocrine secretory pathway. Proposed be a specific endogenous inhibitor of PCSK1. ProSAAS and Big PEN-LEN, both containing the C-terminal inhibitory domain, but not the processed peptides reduce PCSK1 activity in the endoplasmic reticulum and Golgi. It reduces the activity of the 87 kDa form but not the autocatalytically derived 65 kDa form of PCSK1. Subsequent processing of proSAAS may eliminate the inhibition. Slows down convertase-mediated processing of proopiomelanocortin and proenkephalin. May control the intracellular timing of PCSK1 rather than its total level of activity. The function of the processed secreted peptides is not known.


亚细胞位置:
Secreted Golgi apparatus Trans-Golgi network


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