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NUS1 (基因名), Dehydrodolichyl diphosphate synthase complex subunit NUS1 (蛋白名), ngbr_human.
产品名称:

Human NUS1/ Dehydrodolichyl diphosphate synthase complex subunit NUS1 ELISA Kit
NGO-B受体

货号:

E4915h

商标:
EIAab®
监管等级:
别名:

Cis-prenyltransferase subunit NgBR, Nogo-B receptor, Nuclear undecaprenyl pyrophosphate synthase 1 homolog, NgBR, C6orf68, NGBR

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.78-50ng/mL
灵敏度:
0.397ng/mL
特异性:
Natural and recombinant human Dehydrodolichyl diphosphate synthase complex subunit NUS1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Human NUS1 ELISA Kit
规格 & 价格: cart
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Human NUS1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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通用注释


亚单元:
Forms an active dehydrodolichyl diphosphate synthase complex with DHDDS (PubMed:28842490, PubMed:19723497, PubMed:25066056). Interacts with NPC2 (PubMed:21572394).


功能:
With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Both subunits contribute to enzymatic activity, i.e. condensation of multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol phosphate which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER) (PubMed:21572394, PubMed:25066056, PubMed:28842490). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator (PubMed:16835300).


亚细胞位置:
Endoplasmic reticulum membrane Multi-pass membrane protein Colocalizes with Nogo-B during VEGF and wound healing angiogenesis.


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