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NLRP4 (基因名), NACHT, LRR and PYD domains-containing protein 4 (蛋白名), nalp4_human.
产品名称:

Human NLRP4/ NACHT, LRR and PYD domains-containing protein 4 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Cancer/testis antigen 58, PAAD and NACHT-containing protein 2, PYRIN and NACHT-containing protein 2, PYRIN-containing APAF1-like protein 4, Ribonuclease inhibitor 2, CT58, PAN2, PYPAF4, NALP4, PAN2, PYPAF4, RNH2

检测方法:
ELISA
特异性:
Natural and recombinant human NACHT, LRR and PYD domains-containing protein 4
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human NLRP4 ELISA Kit
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Human NLRP4 ELISA Kit
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通用注释


亚单元:
Interacts with CHUK/IKKA, inhibiting its kinase activity.


功能:
May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors. Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1, and its subsequent degradation. Suppresses NF-kappaB induction by the cytokines TNFA and IL1B, suggesting that it operates at a point of convergence in these two cytokine signaling pathways.


亚细胞位置:
N/A


该产品尚未在任何出版物中被引用。
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