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NLRP2 (基因名), NACHT, LRR and PYD domains-containing protein 2 (蛋白名), nalp2_human.
产品名称:

Human NLRP2/ NACHT, LRR and PYD domains-containing protein 2 ELISA Kit
NACHT、LRR和PYD结构域蛋白2

货号:

E14532h

商标:
EIAab®
监管等级:
别名:

Nucleotide-binding site protein 1, PYRIN domain and NACHT domain-containing protein 1, PYRIN-containing APAF1-like protein 2, NALP2, NBS1, PAN1, PYPAF2

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
31.2-2000pg/mL
灵敏度:
15.69pg/mL
特异性:
Natural and recombinant human NACHT, LRR and PYD domains-containing protein 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cancer
Human NLRP2 ELISA Kit
规格 & 价格: cart
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Human NLRP2 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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通用注释


亚单元:
Interacts with CHUK (PubMed:15456791). Interacts with IKBKB (PubMed:15456791). Interacts with IKBKG (PubMed:15456791). Interacts with MEFV (PubMed:17431422). Interacts with PYCARD (PubMed:15030775, PubMed:15456791). Interacts (via pyrin domain) with PYDC2 (PubMed:17178784). Interacts with CARD8 (PubMed:15030775).


功能:
Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.


亚细胞位置:
Cytoplasm


该产品尚未在任何出版物中被引用。
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