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LTN1 (基因名), E3 ubiquitin-protein ligase listerin (蛋白名), ltn1_human.
产品名称:

Human LTN1/ E3 ubiquitin-protein ligase listerin ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

RING finger protein 160, RING-type E3 ubiquitin transferase listerin, Zinc finger protein 294, HSPC087, C21orf10, C21orf98, KIAA0714, RNF160, ZNF294

检测方法:
ELISA
特异性:
Natural and recombinant human E3 ubiquitin-protein ligase listerin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human LTN1 ELISA Kit
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Human LTN1 ELISA Kit
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通用注释


亚单元:
Component of the ribosome quality control complex (RQC), composed of at least the E3 ubiquitin ligase LTN1 and NEMF (PubMed:25578875). The complex probably also contains TCF25 as well as VCP/p97 and its ubiquitin-binding cofactors (By similarity). RQC forms a stable complex with 60S ribosomal subunits (PubMed:25578875).


功能:
E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:23685075, PubMed:25132172, PubMed:25578875). Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product.


亚细胞位置:
N/A


该产品尚未在任何出版物中被引用。
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