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LRIG1 (基因名), Leucine-rich repeats and immunoglobulin-like domains protein 1 (蛋白名), lrig1_human.
产品名称:

Human LRIG1/ Leucine-rich repeats and immunoglobulin-like domains protein 1 ELISA Kit

货号:

E16223h

商标:
EIAab®
监管等级:
别名:

LIG-1, LIG1

检测方法:
ELISA
特异性:
Natural and recombinant human Leucine-rich repeats and immunoglobulin-like domains protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human LRIG1 ELISA Kit
规格 & 价格: cart
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Human LRIG1 ELISA Kit
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通用注释


亚单元:
Interacts (via extracellular LRR and Ig-like domains) with EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 (via extracellular domain) (PubMed:15282549). The physiological relevance of the interaction is controversial; LRIG1 may have low affinity for EGFR, and interaction may occur only when high levels of both proteins are present (PubMed:25765764).


功能:
Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.


亚细胞位置:
Cell membrane Single-pass type I membrane protein


该产品尚未在任何出版物中被引用。
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