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KCNAB1 (基因名), Voltage-gated potassium channel subunit beta-1 (蛋白名), kcab1_chick.
产品名称:

Chicken KCNAB1/ Voltage-gated potassium channel subunit beta-1 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

K(+) channel subunit beta-1, Kv-beta-1, KVB1.1

检测方法:
ELISA
特异性:
Natural and recombinant chicken Voltage-gated potassium channel subunit beta-1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Chicken KCNAB1 ELISA Kit
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Chicken KCNAB1 ELISA Kit
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通用注释


亚单元:
Homotetramer (By similarity). Interaction with tetrameric potassium channel alpha subunits gives rise to a heterooctamer.


功能:
Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits (By similarity). Modulates action potentials via its effect on the pore-forming alpha subunits (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity). Mediates closure of delayed rectifier potassium channels by physically obstructing the pore via its N-terminal domain and increases the speed of channel closure for other family members (By similarity). Binds NADPH; this is required for efficient down-regulation of potassium channel activity (By similarity). Has NADPH-dependent aldoketoreductase activity (By similarity). Oxidation of the bound NADPH strongly decreases N-type inactivation of potassium channel activity.


亚细胞位置:
Cytoplasm Membrane Peripheral membrane protein Cytoplasmic side Cell membrane Peripheral membrane protein Cytoplasmic side Recruited to the cytoplasmic side of the cell membrane via its interaction with pore-forming potassium channel alpha subunits.


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