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JADE2 (基因名), E3 ubiquitin-protein ligase Jade-2 (蛋白名), jade2_human.
产品名称:

Human JADE2/ E3 ubiquitin-protein ligase Jade-2 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Jade family PHD finger protein 2, PHD finger protein 15, KIAA0239, PHF15

检测方法:
ELISA
特异性:
Natural and recombinant human E3 ubiquitin-protein ligase Jade-2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human JADE2 ELISA Kit
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Human JADE2 ELISA Kit
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通用注释


亚单元:
Component of the HBO1 complex composed at least of ING4 or ING5, MYST2/HBO1, MEAF6, and one of JADE1, JADE2 and JADE3 (PubMed:16387653). Interacts (via C-terminus) with KDM1A (via AOD/Tower domain) (PubMed:25018020).


功能:
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo (PubMed:16387653). Acts as a E3 ubiquitin-protein ligase mediating the ubiquitination and subsequent proteasomal degradation of target protein histone demethylase KDM1A (PubMed:25018020). Also acts as a ubiquitin ligase E3 toward itself. Positive regulator of neurogenesis (By similarity).


亚细胞位置:
N/A


该产品尚未在任何出版物中被引用。
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