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Eif2s3 (基因名), Eukaryotic translation initiation factor 2 subunit 3, X-linked (蛋白名), if2g_rat.
产品名称:

Rat Eif2s3/ Eukaryotic translation initiation factor 2 subunit 3, X-linked ELISA Kit

货号:

E11453r

商标:
EIAab®
监管等级:
别名:

Eukaryotic translation initiation factor 2 subunit gamma, X-linked, PP42, eIF-2-gamma, Eif2g, Eif2s3x

检测方法:
ELISA
特异性:
Natural and recombinant rat Eukaryotic translation initiation factor 2 subunit 3, X-linked
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat Eif2s3 ELISA Kit
规格 & 价格: cart
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Rat Eif2s3 ELISA Kit
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通用注释


亚单元:
The eukaryotic translation initiation factor 2 complex/eIF2 is a heterotrimer composed of an alpha subunit, also called subunit 1 (encoded by EIF2S1), a beta subunit, also called subunit 2 (encoded by EIF2S2) and a gamma subunit, also called subunit 3 (encoded by 2 homologous genes Eif2s3x and Eif2s3y).


功能:
As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eIF2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex, a step that determines the rate of protein translation. This step is followed by mRNA binding to form the 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In order for eIF2 to recycle and catalyze another round of initiation, the GDP bound to eIF2 must exchange with GTP by way of a reaction catalyzed by eIF2B (By similarity). Along with its paralog on chromosome X, may contribute to spermatogenesis up to the round spermatid stage.


亚细胞位置:
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