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Hk2 (基因名), Hexokinase-2 (蛋白名), hxk2_rat.
产品名称:

Rat Hk2/ Hexokinase-2 ELISA Kit
己糖激酶-2

货号:

E15354r

商标:
EIAab®
监管等级:
别名:

Hexokinase type II, Hexokinase-B, HK II

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
78-5000pg/mL
灵敏度:
40.3pg/mL
特异性:
Natural and recombinant rat Hexokinase-2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Rat Hk2 ELISA Kit
规格 & 价格: cart
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Rat Hk2 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Monomer (By similarity). Interacts with TIGAR; the interaction increases hexokinase activity in a hypoxia- and HIF1A-dependent manner (By similarity).


功能:
Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively) (PubMed:5871820). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (PubMed:5871820). Plays a key role in maintaining the integrity of the outer mitochondrial membrane by preventing the release of apoptogenic molecules from the intermembrane space and subsequent apoptosis (By similarity).


亚细胞位置:
Mitochondrion outer membrane Peripheral membrane protein Cytoplasm Cytosol The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane. The interaction with the mitochondrial outer membrane via the mitochondrial-binding peptide (MBP) region promotes higher stability of the protein. Release from the mitochondrial outer membrane into the cytosol induces permeability transition pore (PTP) opening and apoptosis.


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