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FGF19 (基因名), Fibroblast growth factor 19 (蛋白名), fgf19_human.
产品名称:

Human FGF19/ Fibroblast growth factor 19 ELISA Kit
纤维母细胞生长因子19

货号:

E15626h

商标:
EIAab®
监管等级:
别名:

UNQ334/PRO533, FGF-19

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
15.6-1000pg/mL
灵敏度:
7.8pg/mL
特异性:
Natural and recombinant human Fibroblast growth factor 19
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cancer
Human FGF19 ELISA Kit
规格 & 价格: cart
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Human FGF19 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

89-99%

96-106%

90-98%

86-96%

EDTA plasma(n=5)

103-112%

103-113%

106-116%

92-102%

heparin plasma(n=5)

101-112%

 

108-116%

109-118%

88-98%

 

通用注释


亚单元:
Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglycans that function as coreceptors. Interacts with KL; this interaction is direct. Interacts with KLB; this interaction is direct. Interacts with FGFR4 in the presence of heparin, KL or KLB. Interacts with MALRD1 (PubMed:23747249).


功能:
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.


亚细胞位置:
Secreted


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