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Ffar4 (基因名), Free fatty acid receptor 4 (蛋白名), ffar4_rat.
产品名称:

Rat Ffar4/ Free fatty acid receptor 4 ELISA Kit
游离脂肪酸受体4

货号:

E15282r

商标:
EIAab®
监管等级:
别名:

G-protein coupled receptor 120, Omega-3 fatty acid receptor 1, Gpr120, O3far1

检测方法:
ELISA
特异性:
Natural and recombinant rat Free fatty acid receptor 4
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat Ffar4 ELISA Kit
规格 & 价格: cart
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Rat Ffar4 ELISA Kit
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通用注释


亚单元:
Interacts with ARRB2 following docosahexaenoic acid (DHA) stimulation.


功能:
Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect, but independent of the G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation.


亚细胞位置:
Cell membrane Multi-pass membrane protein Colocalized with ARRB2 following DHA treatment.


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