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Ero1a (基因名), ERO1-like protein alpha (蛋白名), ero1a_rat.
产品名称:

Rat Ero1a/ ERO1-like protein alpha ELISA Kit

货号:

E6143r

商标:
EIAab®
监管等级:
别名:

Endoplasmic reticulum oxidoreductase alpha, Endoplasmic reticulum oxidoreductin-1-like protein, Global ischemia-induced protein 11, Oxidoreductin-1-L-alpha, ERO1-L, Ero1l, Giig11

检测方法:
ELISA
特异性:
Natural and recombinant rat ERO1-like protein alpha
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat Ero1a ELISA Kit
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Rat Ero1a ELISA Kit
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产品说明书
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通用注释


亚单元:
Predominantly monomer. May function both as a monomer and a homodimer. Interacts with PDILT.


功能:
Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins (By similarity). Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1.


亚细胞位置:
Endoplasmic reticulum membrane Peripheral membrane protein Lumenal side The association with ERP44 is essential for its retention in the endoplasmic reticulum (By similarity). In neurons, it localizes to dendrites.


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