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Ercc1 (基因名), DNA excision repair protein ERCC-1 (蛋白名), ercc1_mouse.
产品名称:

Mouse Ercc1/ DNA excision repair protein ERCC-1 ELISA Kit
切除修复交叉互补因子1

货号:

E1871m

商标:
EIAab®
监管等级:
别名:

Ercc-1

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
39-2500pg/mL
灵敏度:
19.9pg/mL
特异性:
Natural and recombinant mouse DNA excision repair protein ERCC-1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cancer
Mouse Ercc1 ELISA Kit
规格 & 价格: cart
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Mouse Ercc1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Heterodimer composed of ERCC1 and XPF/ERRC4.


功能:
Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.


亚细胞位置:
Nucleus


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