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Erap1 (基因名), Endoplasmic reticulum aminopeptidase 1 (蛋白名), erap1_mouse.
产品名称:

Mouse Erap1/ Endoplasmic reticulum aminopeptidase 1 ELISA Kit
内质网氨基肽酶1

货号:

E12631m

商标:
EIAab®
监管等级:
别名:

ARTS-1, Adipocyte-derived leucine aminopeptidase, Aminopeptidase PILS, Puromycin-insensitive leucyl-specific aminopeptidase, VEGF-induced aminopeptidase, A-LAP, PILS-AP, Appils, Arts1

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.064ng/mL
特异性:
Natural and recombinant mouse Endoplasmic reticulum aminopeptidase 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Mouse Erap1 ELISA Kit
规格 & 价格: cart
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Mouse Erap1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Monomer. May also exist as a heterodimer; with ERAP2. Interacts with RBMX.


功能:
Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.


亚细胞位置:
Endoplasmic reticulum membrane Single-pass type II membrane protein


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