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ENTPD5 (基因名), Ectonucleoside triphosphate diphosphohydrolase 5 (蛋白名), entp5_human.
产品名称:

Human ENTPD5/ Ectonucleoside triphosphate diphosphohydrolase 5 ELISA Kit
核苷三磷酸二磷酸水解酶

货号:

E1978h

商标:
EIAab®
监管等级:
别名:

CD39 antigen-like 4, ER-UDPase, Guanosine-diphosphatase ENTPD5, Nucleoside diphosphatase, Uridine-diphosphatase ENTPD5, GDPase ENTPD5, UDPase ENTPD5, NTPDase 5, CD39L4, PCPH

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.78-50ng/mL
灵敏度:
0.404ng/mL
特异性:
Natural and recombinant human Ectonucleoside triphosphate diphosphohydrolase 5
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cancer
Human ENTPD5 ELISA Kit
规格 & 价格: cart
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Human ENTPD5 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Exists both as a monomer and a disulfide-linked homodimer, the dimers are enzymatically inactive.


功能:
Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.


亚细胞位置:
Endoplasmic reticulum Secreted


该产品尚未在任何出版物中被引用。
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