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Elp3 (基因名), Elongator complex protein 3 (蛋白名), elp3_mouse.
产品名称:

Mouse Elp3/ Elongator complex protein 3 ELISA Kit

货号:

E2706m

商标:
EIAab®
监管等级:
检测方法:
ELISA
特异性:
Natural and recombinant mouse Elongator complex protein 3
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Elp3 ELISA Kit
规格 & 价格: cart
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Mouse Elp3 ELISA Kit
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通用注释


亚单元:
Component of the RNA polymerase II elongator complex (Elongator), which consists of IKBKAP/ELP1, STIP1/ELP2, ELP3, ELP4, ELP5 and ELP6. IKBKAP/ELP1, STIP1/ELP2 and ELP3 form the Elongator core complex. Elongator associates with the C-terminal domain (CTD) of Pol II largest subunit. Interacts with IKBKAP/ELP1 (By similarity). Interacts with alpha-tubulin.


功能:
Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in acetylation of alpha-tubulin (By similarity). May also have a methyltransferase activity. Involved in cell migration. Involved in neurogenesis. Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha-tubulin acetylation (PubMed:19185337).


亚细胞位置:
Cytoplasm Nucleus


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