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Egr1 (基因名), Early growth response protein 1 (蛋白名), egr1_rat.
产品名称:

Rat Egr1/ Early growth response protein 1 ELISA Kit
早期生长反应因子1

货号:

E0416r

商标:
EIAab®
监管等级:
别名:

Nerve growth factor-induced protein A, Transcription factor Zif268, Zinc finger protein Krox-24, NGFI-A, EGR-1

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
78-5000pg/mL
灵敏度:
39.3pg/mL
特异性:
Natural and recombinant rat Early growth response protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Neurosciences
Rat Egr1 ELISA Kit
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Rat Egr1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts with SNAI1 and SP1 upon 12-O-tetradecanoylphorbol-13-acetate (TPA) induction.


功能:
Transcriptional regulator (PubMed:8413279). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity). Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity). Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Activates expression of p53/TP53 and TGFB1, and thereby helps prevent tumor formation. Required for normal progress through mitosis and normal proliferation of hepatocytes after partial hepatectomy. Mediates responses to ischemia and hypoxia; regulates the expression of proteins such as IL1B and CXCL2 that are involved in inflammatory processes and development of tissue damage after ischemia. Regulates biosynthesis of luteinizing hormone (LHB) in the pituitary.


亚细胞位置:
Nucleus Cytoplasm


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