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EFNA5 (基因名), Ephrin-A5 (蛋白名), efna5_chick.
产品名称:

Chicken EFNA5/ Ephrin-A5 ELISA Kit

货号:

E10772c

商标:
EIAab®
监管等级:
别名:

EPH-related receptor tyrosine kinase ligand 7, Repulsive axon guidance signal protein, LERK-7, RAGS

检测方法:
ELISA
特异性:
Natural and recombinant chicken Ephrin-A5
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Chicken EFNA5 ELISA Kit
规格 & 价格: cart
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Chicken EFNA5 ELISA Kit
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亚单元:
N/A


功能:
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Induces compartmentalized signaling within a caveolae-like membrane microdomain when bound to the extracellular domain of its cognate receptor. This signaling event requires the activity of the Fyn tyrosine kinase. Activates the EPHA3 receptor to regulate cell-cell adhesion and cytoskeletal organization. With the receptor EPHA2 may regulate lens fiber cells shape and interactions and be important for lens transparency maintenance. May function actively to stimulate axon fasciculation (By similarity). Induces growth cone collapse and repulsion of retinal ganglion cell axons.


亚细胞位置:
Cell membrane Lipid-anchor GPI-anchor


该产品尚未在任何出版物中被引用。
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