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Edem1 (基因名), ER degradation-enhancing alpha-mannosidase-like protein 1 (蛋白名), edem1_mouse.
产品名称:

Mouse Edem1/ ER degradation-enhancing alpha-mannosidase-like protein 1 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Edem

检测方法:
ELISA
特异性:
Natural and recombinant mouse ER degradation-enhancing alpha-mannosidase-like protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Edem1 ELISA Kit
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Mouse Edem1 ELISA Kit
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通用注释


亚单元:
Interacts with DERL2 and DERL3. Binds to SEL1L (By similarity). Interacts with DNAJC10.


功能:
Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.


亚细胞位置:
Endoplasmic reticulum membrane Single-pass type II membrane protein


该产品尚未在任何出版物中被引用。
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