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DDX39B (基因名), Spliceosome RNA helicase DDX39B (蛋白名), dx39b_canfa.
产品名称:

Dog DDX39B/ Spliceosome RNA helicase DDX39B ELISA Kit

货号:

E14263d

商标:
EIAab®
监管等级:
别名:

56 kDa U2AF65-associated protein, DEAD box protein UAP56, BAT1, UAP56

检测方法:
ELISA
特异性:
Natural and recombinant dog Spliceosome RNA helicase DDX39B
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Dog DDX39B ELISA Kit
规格 & 价格: cart
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Dog DDX39B ELISA Kit
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通用注释


亚单元:
Homodimer, and heterodimer with DDX39A. Component of the THO complex, which is composed of THOC1, THOC2, THOC5, THOC6 and THOC7. Together with THOC3, THOC4 and DDX39B, THO forms the transcription/export (TREX) complex. Component of the spliceosome. Interacts directly with U2AF2. Interacts directly with THOC4 and is necessary for THOC4 recruitment to spliced mRNA. Interacts with RBM8A, RNPS1 and SRRM1. Interacts with FYTTD1/UIF and THOC1.


功能:
Splice factor that is required for the first ATP-dependent step in spliceosome assembly and for the interaction of U2 snRNP with the branchpoint. Has both RNA-stimulated ATP binding/hydrolysis activity and ATP-dependent RNA unwinding activity. Even with the stimulation of RNA, the ATPase activity is weak. Can only hydrolyze ATP but not other NTPs. The RNA stimulation of ATPase activity does not have a strong preference for the sequence and length of the RNA. However, ssRNA stimulates the ATPase activity much more strongly than dsRNA. The ATPase and helicase activities are not influenced by U2AF2 and THOC4.


亚细胞位置:
Nucleus Nucleus speckle


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