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Dok7 (基因名), Protein Dok-7 (蛋白名), dok7_mouse.
产品名称:

Mouse Dok7/ Protein Dok-7 ELISA Kit

货号:

E11781m

商标:
EIAab®
监管等级:
别名:

Downstream of tyrosine kinase 7

检测方法:
ELISA
特异性:
Natural and recombinant mouse Protein Dok-7
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Dok7 ELISA Kit
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Mouse Dok7 ELISA Kit
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通用注释


亚单元:
Homodimer. Forms a heterotetramer composed of 2 DOK7 and 2 MUSK molecules which facilitates MUSK trans-autophosphorylation on tyrosine residue and activation. Interacts (via IRS-type PTB domain) with MUSK (via cytoplasmic part); requires MUSK phosphorylation.


功能:
Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.


亚细胞位置:
Cell membrane Peripheral membrane protein Cell junction Synapse Accumulates at neuromuscular junctions.


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