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Dnase1l3 (基因名), Deoxyribonuclease gamma (蛋白名), dnsl3_rat.
产品名称:

Rat Dnase1l3/ Deoxyribonuclease gamma ELISA Kit
脱氧核糖核酸酶γ

货号:

E2661r

商标:
EIAab®
监管等级:
别名:

DNaseY, Deoxyribonuclease I-like 3, DNase I-like 3, DNase gamma

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/mL
灵敏度:
0.184ng/mL
特异性:
Natural and recombinant rat Deoxyribonuclease gamma
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Epigenetics
Rat Dnase1l3 ELISA Kit
规格 & 价格: cart
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Monomer.


功能:
Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends (PubMed:7957253). Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA. Acts in internucleosomal DNA fragmentation (INDF) during apoptosis and necrosis. The role in apoptosis includes myogenic and neuronal differentiation, and BCR-mediated clonal deletion of self-reactive B cells. Is active on chromatin in apoptotic cell-derived membrane-coated microparticles and thus suppresses anti-DNA autoimmunity.


亚细胞位置:
Nucleus Secreted May first pass through the ER membrane before being imported in the nucleus. Contradictory reports exist about the subcellular localization under normal physiological conditions. Under conditions of cell death, may diffuse and/or be actively transported to the nucleus (By similarity).


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