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Ddr2 (基因名), Discoidin domain-containing receptor 2 (蛋白名), ddr2_mouse.
产品名称:

Mouse Ddr2/ Discoidin domain-containing receptor 2 ELISA Kit
盘状蛋白结构域受体2

货号:

E1505m

商标:
EIAab®
监管等级:
别名:

CD167 antigen-like family member B, Neurotrophic tyrosine kinase, receptor-related 3, Receptor protein-tyrosine kinase TKT, Tyrosine-protein kinase TYRO10, CD167b, Discoidin domain receptor 2, Ntrkr3, Tkt, Tyro10

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.093ng/mL
特异性:
Natural and recombinant mouse Discoidin domain-containing receptor 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Mouse Ddr2 ELISA Kit
规格 & 价格: cart
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Mouse Ddr2 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Binds hydroxyproline-rich sequence motifs in fibrillar, glycosylated collagen, such as the GQOGVMGFO motif, where O stands for hydroxyproline. Interacts with SRC. Interacts (tyrosine phosphorylated) with SHC1.


功能:
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.


亚细胞位置:
Cell membrane Single-pass type I membrane protein


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