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CUL5 (基因名), Cullin-5 (蛋白名), cul5_human.
产品名称:

Human CUL5/ Cullin-5 ELISA Kit
Cullin-5

货号:

E15273h

商标:
EIAab®
监管等级:
别名:

Vasopressin-activated calcium-mobilizing receptor 1, VACM-1, CUL-5, VACM1

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/mL
灵敏度:
0.176ng/mL
特异性:
Natural and recombinant human Cullin-5
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cancer
Human CUL5 ELISA Kit
规格 & 价格: cart
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Human CUL5 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
(Microbial infection) The substrate recognition component can also be a viral protein such as HIV Vif, or human adenovirus 5 E1B large T-antigen and E4-orf6.


功能:
Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.


亚细胞位置:
N/A


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