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Nedd9 (基因名), Enhancer of filamentation 1 (蛋白名), casl_mouse.
产品名称:

Mouse Nedd9/ Enhancer of filamentation 1 ELISA Kit
细丝增强子1

货号:

E15036m

商标:
EIAab®
监管等级:
别名:

CRK-associated substrate-related protein, Neural precursor cell expressed developmentally down-regulated protein 9, p105, CAS-L, NEDD-9, mEF1, Casl

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.064ng/mL
特异性:
Natural and recombinant mouse Enhancer of filamentation 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cancer
Mouse Nedd9 ELISA Kit
规格 & 价格: cart
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Mouse Nedd9 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

96-106%

112-122%

82-92%

80-89%

EDTA plasma(n=5)

90-98%

89-99%

95-105%

104-114%

heparin plasma(n=5)

97-107%

 

91-101%

110-120%

104-113%

 

通用注释


亚单元:
Homodimer. Can heterodimerize with HLH proteins ID2, E12, E47 and also with p130cas. Forms complexes in vivo with related adhesion focal tyrosine kinase (RAFTK), adapter protein CRKL and LYN kinase. Interacts with MICAL and TXNL4/DIM1 (By similarity). Interacts with BCAR3 and SH2D3C.


功能:
Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B- and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form.


亚细胞位置:
Cytoplasm Cell cortex Nucleus Cytoplasm Cytoskeleton Localizes to both the cell nucleus and the cell periphery.


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