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BCL2 (基因名), Apoptosis regulator Bcl-2 (蛋白名), bcl2_canfa.
产品名称:

Dog BCL2/ Apoptosis regulator Bcl-2 ELISA Kit
细胞凋亡调整器Bcl-2

货号:

E0778d

商标:
EIAab®
监管等级:
检测方法:
ELISA
特异性:
Natural and recombinant dog Apoptosis regulator Bcl-2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Neurosciences
Dog BCL2 ELISA Kit
规格 & 价格: cart
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Dog BCL2 ELISA Kit
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通用注释


亚单元:
Forms homodimers, and heterodimers with BAX, BAD, BAK and Bcl-X(L). Heterodimerization with BAX requires intact BH1 and BH2 motifs, and is necessary for anti-apoptotic activity. Also interacts with FKBP8, APAF1, RAF-1, TP53BP2, BBC3, BCL2L1, MRPL41 and BNIPL. Interacts with BAG1 in an ATP-dependent manner.


功能:
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).


亚细胞位置:
Mitochondrion outer membrane Single-pass membrane protein Nucleus membrane Single-pass membrane protein Endoplasmic reticulum membrane Single-pass membrane protein


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