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Bcar1 (基因名), Breast cancer anti-estrogen resistance protein 1 (蛋白名), bcar1_mouse.
产品名称:

Mouse Bcar1/ Breast cancer anti-estrogen resistance protein 1 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

CRK-associated substrate, p130cas, Cas, Crkas

检测方法:
ELISA
特异性:
Natural and recombinant mouse Breast cancer anti-estrogen resistance protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cancer
Mouse Bcar1 ELISA Kit
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Mouse Bcar1 ELISA Kit
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通用注释


亚单元:
Forms complexes in vivo with PTK2/FAK1, adapter protein CRKL and LYN kinase. Can heterodimerize with NEDD9. Interacts with activated CSPG4. Interacts with BMX, INPPL1/SHIP2 and PEAK1 (By similarity). Part of a collagen stimulated complex involved in cell migration composed of CDC42, CRK, TNK2 and BCAR1/p130cas (By similarity). Interacts with BCAR3, the interaction regulates adhesion-dependent serine phosphorylation. Interacts with NPHP1, PTK2B/PYK2 and SH2D3C.


功能:
Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration (By similarity). Has been shown to be essential in cardiovascular development during embryogenesis.


亚细胞位置:
Cell junction Focal adhesion Cytoplasm Unphosphorylated form localizes in the cytoplasm and can move to the membrane upon tyrosine phosphorylation.


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