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BAIAP3 (基因名), BAI1-associated protein 3 (蛋白名), baip3_human.
产品名称:

Human BAIAP3/ BAI1-associated protein 3 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Brain-specific angiogenesis inhibitor I-associated protein 3, BAP3, KIAA0734

检测方法:
ELISA
特异性:
Natural and recombinant human BAI1-associated protein 3
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human BAIAP3 ELISA Kit
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Human BAIAP3 ELISA Kit
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通用注释


亚单元:
Interacts with ADGRB1; this interaction is direct (PubMed:9790924). Interacts with endosomal SNARE proteins VAMP3, VAMP4, STX6 and STX16; this interaction is increased in the presence of calcium (PubMed:28626000).


功能:
Functions in endosome to Golgi retrograde transport. In response to calcium influx, may interact with SNARE fusion receptors and membrane phospholipids to mediate endosome fusion with the trans-Golgi network. By promoting the recycling of secretory vesicle transmembrane proteins, it indirectly controls dense-core secretory vesicle biogenesis, maturation and their ability to mediate the constitutive and regulated secretion of neurotransmitters and hormones. May regulate behavior and food intake by controlling calcium-stimulated exocytosis of neurotransmitters including NPY and serotonin and hormones like insulin (PubMed:28626000). Proposed to play a role in hypothalamic neuronal firing by modulating gamma-aminobutyric acid (GABA)ergic inhibitory neurotransmission (By similarity).


亚细胞位置:
Cytoplasm Cytosol Recycling endosome membrane Peripheral membrane protein Late endosome membrane Peripheral membrane protein Golgi apparatus Trans-Golgi network membrane Peripheral membrane protein Cell membrane Peripheral membrane protein Rapidly recruited to the plasma membrane and to Golgi structures in response to increased intracellular calcium concentration.


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