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PRMT7 (基因名), Protein arginine N-methyltransferase 7 (蛋白名), anm7_chick.
产品名称:

Chicken PRMT7/ Protein arginine N-methyltransferase 7 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Histone-arginine N-methyltransferase PRMT7, [Myelin basic protein]-arginine N-methyltransferase PRMT7, RCJMB04_28e13

检测方法:
ELISA
特异性:
Natural and recombinant chicken Protein arginine N-methyltransferase 7
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Chicken PRMT7 ELISA Kit
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Chicken PRMT7 ELISA Kit
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亚单元:
N/A


功能:
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.


亚细胞位置:
Cytoplasm Cytosol Nucleus


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