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ANG (基因名), Angiogenin (蛋白名), angi_chick.
产品名称:

Chicken ANG/ Angiogenin ELISA Kit
血管生长素

货号:

E0007c

商标:
EIAab®
监管等级:
别名:

Ribonuclease A

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
78-5000pg/mL
灵敏度:
39pg/mL
特异性:
Natural and recombinant chicken Angiogenin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Chicken ANG ELISA Kit
规格 & 价格: cart
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Chicken ANG ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Homodimer. Interacts with and forms a tight 1:1 complex with RNH1. Dimerization of two such complexes may occur.


功能:
Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.


亚细胞位置:
Cytoplasmic vesicle Secretory vesicle lumen Secreted Nucleus Nucleolus Rapidly endocytosed by target cells and translocated to the nucleus where it accumulates in the nucleolus and binds to DNA (By similarity).


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