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TXN (基因名), Thioredoxin (蛋白名), THIO_CANFA.
产品名称:

Dog TXN/ Thioredoxin ELISA Kit
硫氧化还原蛋白

货号:

E0702d

商标:
EIAab®
监管等级:
别名:

Trx

检测方法:
ELISA
实验类型:
Sandwich
特异性:
Natural and recombinant dog Thioredoxin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Epigenetics
Dog TXN ELISA Kit
规格 & 价格: cart
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Dog TXN ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

106-115%

90-99%

94-104%

91-104%

EDTA plasma(n=5)

93-102%

105-115%

90-102%

109-118%

heparin plasma(n=5)

102-110%

 

97-107%

106-116%

83-93%

 

通用注释


亚单元:
Homodimer; disulfide-linked. Interacts with TXNIP through the redox-active site. Interacts with MAP3K5 and CASP3. Interacts with APEX1; the interaction stimulates the FOS/JUN AP-1 DNA-binding activity in a redox-dependent manner.


功能:
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.


亚细胞位置:
Nucleus Cytoplasm Secreted Secreted by a leaderless secretory pathway. Predominantly in the cytoplasm in non irradiated cells. Radiation induces translocation of TRX from the cytoplasm to the nucleus.


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