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Sfrp1 (基因名), Secreted frizzled-related protein 1 (蛋白名), SFRP1_RAT.
产品名称:

Rat Sfrp1/ Secreted frizzled-related protein 1 ELISA Kit
分泌卷曲相关蛋白

货号:

E1165r

商标:
EIAab®
监管等级:
别名:

sFRP-1

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.625-40ng/mL
灵敏度:
0.328ng/mL
特异性:
Natural and recombinant rat Secreted frizzled-related protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cancer
Rat Sfrp1 ELISA Kit
规格 & 价格: cart
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Rat Sfrp1 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts with WNT4, WNT1, WNT2, WNT8, MYOC and FRZD6.


功能:
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase. In kidney development, inhibits tubule formation and bud growth in metanephroi. Inhibits WNT1/WNT4-mediated TCF-dependent transcription.


亚细胞位置:
Secreted Cell membrane or extracellular matrix-associated. Released by heparin-binding (By similarity).


该产品尚未在任何出版物中被引用。
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