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Hspb6 (基因名), Heat shock protein beta-6 (蛋白名), HSPB6_RAT.
产品名称:

Rat Hspb6/ Heat shock protein beta-6 ELISA Kit
热休克蛋白B6

货号:

E0871r

商标:
EIAab®
监管等级:
别名:

Heat shock 20 kDa-like protein p20, HspB6

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.625-40ng/mL
灵敏度:
0.335ng/mL
特异性:
Natural and recombinant rat Heat shock protein beta-6
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cancer
Rat Hspb6 ELISA Kit
规格 & 价格: cart
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Rat Hspb6 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Homodimer (PubMed:19646995). Small heat shock proteins form high molecular mass oligomers containing variable number of monomers; these oligomers display a very flexible quaternary structure easily exchanging their subunits. Heterooligomer with HSPB1; formed through oligomerization of HSPB1:HSBP6 dimers; subunit exchange leads to formation of at least two different heterooligomeric complexes, differing in variable quantities of HSPB1 and HSPB6 homodimers in addition to HSPB1:HSPB6 heterodimers. Heterooligomer with CRYAB; large heterooligomers consist of CRYAB homodimers and HSPB5:HSPB6 heterodimers but lacking HSPB6 homodimers. Interacts with BAG3. Interacts (phosphorylated) with YWHAZ. Interacts with PDE4A and PDE4D; required for maintenance of the non-phosphorylated state of HSPB6 under basal conditions. Interacts with KDR. Interacts with PRKD1.


功能:
Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity.


亚细胞位置:
Cytoplasm Nucleus Secreted Translocates to nuclear foci during heat shock.


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