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Btf3 (基因名), Transcription factor BTF3 (蛋白名), BTF3_MOUSE.
产品名称:

Mouse Btf3/ Transcription factor BTF3 ELISA Kit
转录因子BTF3

货号:

E15257m

商标:
EIAab®
监管等级:
别名:

Nascent polypeptide-associated complex subunit beta, RNA polymerase B transcription factor 3, NAC-beta

检测方法:
ELISA
特异性:
Natural and recombinant mouse Transcription factor BTF3
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Epigenetics
Mouse Btf3 ELISA Kit
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Mouse Btf3 ELISA Kit
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通用注释


亚单元:
Part of the nascent polypeptide-associated complex (NAC), which is a heterodimer of NACA and BTF3 (via NAC-A/B domains). NAC associates with ribosomes through the BTF3/NACB subunit. Both subunits can contact nascent polypeptide chains.


功能:
When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription.


亚细胞位置:
Cytoplasm Nucleus The heterodimer with NACA is cytoplasmic.


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