Human ZC3H12A/ Endoribonuclease ZC3H12A CLIA Kit

货号:

U15785h

商标:

EIAab^®

监管等级:

RUO

别名:

Monocyte chemotactic protein-induced protein 1, Regnase-1, Zinc finger CCCH domain-containing protein 12A, MCP-induced protein 1, Reg1, MCPIP, MCPIP1

检测方法:

CLIA

特异性:

Natural and recombinant human Endoribonuclease ZC3H12A

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Immunology

规格 & 价格:

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Human ZC3H12A CLIA Kit

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通用注释

亚单元:

(Microbial infection) Oligomerization is necessary for antiviral activity (PubMed:23355615).

功能:

(Microbial infection) Exhibits broad antiviral activity by cleaving viral RNAs (PubMed:23355615). Binds to Japanese encephalitis virus (JEV) and dengue virus (DEN) RNAs (PubMed:23355615). Exhibits antiviral activity against HIV-1 in lymphocytes by decreasing the abundance of HIV-1 viral RNA species (PubMed:24191027).

亚细胞位置:

Nucleus Cytoplasm Cytoplasm P-body Rough endoplasmic reticulum membrane Peripheral membrane protein Cytoplasmic side Cytoplasmic granule Predominantly localized in the cytoplasm. Colocalizes with GW182 on many granule-like structures, probably corresponding to cytoplasmic GW bodies (GWBs), also called processing bodies (P bodies). Colocalizes with calnexin on the surface of the rough endoplasmic reticulum (RER) membrane and with translationally active polysomes (By similarity). Colocalizes with ZC3H12D in cytoplasmic mRNA processing P-body, also known as GW bodies (GWBs) (PubMed:22055188, PubMed:26134560).

数据库链接

UniGene:

Hs.656294

SMR:

Q5D1E8

STRING:

9606.ENSP00000362174

KEGG:

hsa:80149

MIM:

610562

Pfam: