YAP1 (基因名), Transcriptional coactivator YAP1 (蛋白名), yap1_chick.
产品名称:
Chicken YAP1/ Transcriptional coactivator YAP1 CLIA Kit
约克同源
货号:
U15210c
商标:
EIAab®
监管等级:
别名:
65 kDa Yes-associated protein, Protein yorkie homolog, YAP65, Yes-associated protein 1, YAP65
检测方法:
CLIA
特异性:
Natural and recombinant chicken Transcriptional coactivator YAP1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
N/A
功能:
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation.
亚细胞位置:
Cytoplasm
Nucleus
Both phosphorylation and cell density can regulate its subcellular localization. Phosphorylation sequesters it in the cytoplasm by inhibiting its translocation into the nucleus. At low density, predominantly nuclear and is translocated to the cytoplasm at high density.
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