Mouse Wdr1/ WD repeat-containing protein 1 CLIA Kit

货号:

U14349m

商标:

EIAab^®

监管等级:

RUO

别名:

Actin-interacting protein 1, AIP1

检测方法:

CLIA

特异性:

Natural and recombinant mouse WD repeat-containing protein 1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Mouse Wdr1 CLIA Kit

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通用注释

亚单元:

N/A

功能:

Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins (By similarity). Enhances cofilin-mediated actin severing (PubMed:25915128). Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions (By similarity). Involved in myocardium sarcomere organization. Required for cardiomyocyte growth at the postnatal and maintenance at the adult stage (PubMed:24840128). Involved in neutrophil actin dynamics and migration. Involved in megakaryocyte maturation and platelet shedding (PubMed:17515402). Required for the establishment of planar cell polarity (PCP) during follicular epithelium development and for cell shape changes during PCP; the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension (PubMed:25915128). Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt.

亚细胞位置:

Cytoplasm Cytoskeleton Cell projection Podosome

数据库链接

UniGene:

Mm.2654

SMR:

O88342

STRING:

10090.ENSMUSP00000005234

KEGG:

mmu:22388

Pfam: