VEGFA (基因名), Vascular endothelial growth factor A (蛋白名), vegfa_bovin.
产品名称:
Bovine VEGFA/ Vascular endothelial growth factor A CLIA Kit
血管内皮生长因子A
货号:
U0143b
商标:
EIAab®
监管等级:
别名:
Vascular permeability factor, VPF, VEGF-A, VEGF
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
3.9-250pg/mL
特异性:
Natural and recombinant bovine Vascular endothelial growth factor A
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
Cancer
精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: 3.9%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: 7.7%
批内 CV: 3.9%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: 7.7%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。
Sample Type |
Average(%) |
Recovery Range(%) |
Serum |
99 |
91-103 |
Plasma |
98 |
93-106 |
线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。
Sample |
1:2 |
1:4 |
1:8 |
1:16 |
serum(n=5) |
92-105% |
90-101% |
95-105% |
92-109% |
EDTA plasma(n=5) |
89-95% |
93105% |
89-94% |
90-106% |
heparin plasma(n=5) |
93-104%
|
94-110% |
101-111% |
91-110% |
通用注释
亚单元:
Homodimer; disulfide-linked. Also found as heterodimer with PGF (By similarity). Interacts with NRP1.
功能:
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development.
亚细胞位置:
Secreted
Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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