VDR (基因名), Vitamin D3 receptor (蛋白名), vdr_bovin.
产品名称:
Bovine VDR/ Vitamin D3 receptor CLIA Kit
维生素D3受体
货号:
U0475b
商标:
EIAab®
监管等级:
别名:
1, 25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, VDR, NR1I1
检测方法:
CLIA
特异性:
Natural and recombinant bovine Vitamin D3 receptor
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
Homodimer in the absence of bound vitamin D3. Heterodimer with RXRA after vitamin D3 binding. Interacts with SMAD3. Interacts with MED1, NCOA1, NCOA2, NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Interacts (in a ligand-dependent manner) with BAZ1B/WSTF. Interacts with SNW1. Interacts with IRX4, the interaction doesn't affect its transactivation activity.
功能:
Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
亚细胞位置:
Nucleus
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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