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VAPB (基因名), Vesicle-associated membrane protein-associated protein B/C (蛋白名), vapb_human.

产品名称:

Human VAPB/ Vesicle-associated membrane protein-associated protein B/C CLIA Kit

货号:

U11939h

商标:

EIAab^®

监管等级:

RUO

别名:

UNQ484/PRO983, VAMP-B/VAMP-C

检测方法:

CLIA

特异性:

Natural and recombinant human Vesicle-associated membrane protein-associated protein B/C

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cardiovascular

规格 & 价格:

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通用注释

亚单元:

Homodimer, and heterodimer with VAPA (PubMed:20940299). Interacts with VAMP1 and VAMP2 (PubMed:9920726, PubMed:20940299). Interacts with HCV NS5A and NS5B (PubMed:16227268). Interacts (via MSP domain) with ZFYVE27 (PubMed:21976701, PubMed:19289470). Interacts with RMDN3 (PubMed:22131369). Interacts with KIF5A in a ZFYVE27-dependent manner (PubMed:21976701).

功能:

Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.

亚细胞位置:

Endoplasmic reticulum membrane Single-pass type IV membrane protein Present in mitochondria-associated membranes that are endoplasmic reticulum membrane regions closely apposed to the outer mitochondrial membrane.

数据库链接

UniGene:

Hs.182625

SMR:

O95292

STRING:

9606.ENSP00000417175

KEGG:

hsa:9217

MIM:

182980

Pfam: