ULBP1 (基因名), UL16-binding protein 1 (蛋白名), ulbp1_human.
产品名称:
Human ULBP1/ UL16-binding protein 1 CLIA Kit
UL16-binding蛋白1
货号:
U3031h
商标:
EIAab®
监管等级:
别名:
ALCAN-beta, NKG2D ligand 1, Retinoic acid early transcript 1I, N2DL-1, N2DL1, RAET1I
检测方法:
CLIA
特异性:
Natural and recombinant human UL16-binding protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Immunology
通用注释
亚单元:
(Microbial infection) In CMV-infected cells, interacts with the viral glycoprotein UL16; this interaction causes ULBP1 retention in the endoplasmic reticulum and cis-Golgi and prevents binding to and activation of KLRK1/NKG2D, providing CMV with an immune evasion mechanism.
功能:
Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.
亚细胞位置:
Cell membrane
Lipid-anchor
GPI-anchor
Endoplasmic reticulum
In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi.
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