TAPBP (基因名), Tapasin (蛋白名), tpsn_canfa.
通用注释
亚单元:
Interacts with TAP1 and is thus a subunit of the TAP complex. Interaction with TAP1 is TAP2 independent and is required for efficient peptide-TAP interaction. Obligatory mediator for the interaction between newly assembled MHC class I molecules, clareticulin, ERp57 and TAP. Up to 4 MHC class I/tapasin complexes bind to 1 TAP.
功能:
Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
亚细胞位置:
Endoplasmic reticulum membrane
Single-pass type I membrane protein
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