TFRC (基因名), Transferrin receptor protein 1 (蛋白名), tfr1_canfa.
产品名称:
Dog TFRC/ Transferrin receptor protein 1 CLIA Kit
转铁蛋白受体蛋白1
货号:
U0809d
商标:
EIAab®
监管等级:
别名:
CD71, TR, TfR, TfR1, Trfr
检测方法:
CLIA
特异性:
Natural and recombinant dog Transferrin receptor protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Neurosciences
通用注释
亚单元:
Homodimer; disulfide-linked. Binds one transferrin molecule per subunit. Interacts with SH3BP4.
功能:
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system.
亚细胞位置:
Cell membrane
Single-pass type II membrane protein
Melanosome
验证序列:
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