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Tab3 (基因名), TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (蛋白名), tab3_mouse.

产品名称:

Mouse Tab3/ TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 CLIA Kit
磷酸化转化生长因子β活化激酶结合蛋白3

货号:

U2881m

商标:

EIAab^®

监管等级:

RUO

别名:

Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, TAK1-binding protein 3, TGF-beta-activated kinase 1-binding protein 3, TAB-3, Kiaa4135, Map3k7ip3

检测方法:

CLIA

特异性:

Natural and recombinant mouse TGF-beta-activated kinase 1 and MAP3K7-binding protein 3

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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通用注释

亚单元:

Interacts with TAB1, TAB2, MAP3K7, TRAF2 and TRAF6. The minimal TAB3-containing complex (TAB1-MAP3K7-TAB3) appears not to contain TAB2. However, it seems sensible to consider that TAB2 may also join this complex and may act in a cooperative manner with TAB3. Interacts with WDR34 (via the WD domains). Binds 'Lys-63'-linked polyubiquitin chains. Interacts with RBCK1 (By similarity). Interacts with TRIM5.

功能:

Adapter linking MAP3K7/TAK1 and TRAF6 or TRAF2. Mediator of MAP3K7 activation, respectively in the IL-1 and TNF signaling pathways. Plays a role in activation of NF-kappa-B and AP1 transcription factor.

亚细胞位置:

N/A

数据库链接

UniGene:

Mm.119646

SMR:

Q571K4

STRING:

10090.ENSMUSP00000039668

KEGG:

mmu:66724

Pfam: